From the South (Sea-Tac Airport):
Take I-5 northbound. Take Seneca street exit. Follow Seneca street west until you reach First Avenue. Turn right on First Avenue (heading north). Go straight up First Avenue about 10 blocks. They are located on the left-hand side of First Avenue at the southwest corner of First Avenue & Wall Street. Entrance is on First Avenue, at street level, near the Cyclops Bar entrance. Check out my blog for the "backdoor" route to the city or wait until 2010 for light rail from the airport. Ask your taxi driver to take the backdoor route as traffic can delay you and add time and dollars to your meter.
From the North (Vancouver, BC):
Take I-5 southbound. Take Stewart/Denny exit. Follow Stewart Street down to First Avenue. Turn right on First Avenue and go a few blocks north. They are located on the left-hand side of First Avenue at the southwest corner of First Avenue & Wall Street. The entrance is on First Avenue, at street level, near the Cyclops Bar entrance.