From the South / Seattle-Tacoma Airport:
Take Interstate 5 North into Seattle, WA.
Exit at Madison Street.
Turn left at first stoplight. This is Madison Street.
Follow Madison Street to First Avenue.
The downtown Alexis Hotel is on the corner at the intersection of First Avenue and Madison Street.
From the North:
Take Interstate 5 South to downtown Seattle, WA.
Exit at James Street; get in the right lane and turn right onto James Street.
Take James Street to First Avenue; turn right onto First.
Turn left on Madison Street.
The luxury downtown Alexis Hotel is down the corner of First Avenue and Madison Street.